Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetActin polymerization

General description

A structurally unique marine toxin. Inhibits actin polymerization in vitro and disrupts microfilament organization as well as microfilament-mediated processes. 10 to 100-fold more potent than cytochalasins.

A structurally unique marine toxin. Inhibits actin polymerization in vitro and disrupts microfilament organization as well as microfilament-mediated processes; 10 to 100-fold more potent than cytochalasins.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Spector, I., et al. 1989. Cell Motil. Cytoskeleton13, 127.de Oliveira, C.A., and Mantovani, B. 1988. Life Sci.43, 1825.Coue, M., et al. 1987. FEBS Lett.213, 316.Spector, I., et al. 1983. Science219, 493.

Packaging

1, 5 mg in Plastic ampoule

Warning

Toxicity: Harmful (C)